

From a stability standpoint, lithopone, a fusion of zinc sulfide and artificially precipitated barite, is non-toxic and exhibits resilience to mild lyes and acids. However, it is incompatible with colors containing copper. Despite its strong covering power in oil, lithopone’s drying capabilities are notably limited, posing potential issues for artists. Notably, early experimentation with lithopone-based grounds instead of zinc white resulted in undesirable darkening, although this blackness receded upon drying. This unpredictable behavior has sparked debate among scientific communities, emphasizing the need for further exploration and understanding of this pigment.
Titanium dioxide is a widely used white pigment in various applications such as paint, coatings, plastics, paper, and even food products. It is known for its brightness and high refractive index, making it the preferred choice for imparting opacity and whiteness in many products.The Chinese titanium dioxide industry boasts advanced technologies including the chloride process and the sulfate process. The chloride process is favored for its higher quality product suitable for applications in paints, coatings, and plastics, while the sulfate process is cost-effective and widely used for products like paper and fibers. Innovation and technological upgrades continue to be key drivers for enhancing production efficiency and product quality.
Recent analyses of food-grade TiO2 samples have found that a significant portion of particles may be within the nanoscale. These particles (also known as nanoparticles) range in size from 1 to 100 nm, where 1 nm equals 1 billionth of a metre (the width of a typical human hair is 80,000 to 100,000 nm).
The particle size and shape of anatase TiO2 play a crucial role in its performance in various applications

At the present JECFA meeting, the committee considered additional toxicological studies relevant to the safety assessment of the chemical that investigated its toxicokinetics, acute toxicity, short-term toxicity, long-term toxicity and carcinogenicity, genotoxicity, and reproductive and developmental toxicity, as well as special studies addressing its short-term initiation/promotion potential for colon cancer. The experts acknowledged that a large number of toxicological studies have been conducted using test materials, including nanoparticles, having size distributions and physico-chemical properties not comparable to real-world uses of titanium dioxide as a food additive. The studies on non-representative materials were evaluated by JECFA, but the committee concluded that such studies are not relevant to the safety assessment of the additive.
Lithopone, a zinc sulfide-based pigment, has been widely used in various industries due to its excellent whiteness, opacity, and chemical stability. Among the various grades of lithopone, 28B301 and 30B311 are particularly popular among manufacturers. In this article, we will provide a comprehensive guide on these two grades, including their properties, applications, and manufacturing processes.
For First, Second and Third Quarters of 2021
if you compare the levels—which went as high as 50,000 milligrams/killigrams per day— to what humans are actually exposed to, we're talking orders of magnitude. It was a huge amount, Norbert Kaminski, PhD, a professor of pharmacology & toxicology and director of the Center for Research on Ingredient Safety at Michigan State University told Health.